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Cullin 3 antibody

WebMay 12, 2024 · MLN4924, a neddylation inhibitor of Cullin-Ring E3 ligases, dramatically reduced the proliferation of tumor cells, especially CUL3-overexpressing cells, which showed that BECN1 degradation mediated by CUL3 could be an effective therapeutic target for breast cancer. Results BECN1 protein level is regulated through the ubiquitin … WebThe BTB protein serves as a bridge to connect Cul3 to substrate and is functionally equivalent to the combination of substrate adaptor and linker in other Cullin complexes. …

Cullin 3 monoclonal antibody Western, Immunoprecipitation …

WebThe E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit … WebView Rabbit Polyclonal anti-Cullin 3 Antibody (NBP2-92848). Validated Applications: WB, ICC/IF. Validated Species: Human, Mouse, Rat. Sample size available. how to smoke kief without bud https://mantei1.com

CUL1 Antibody Cell Signaling Technology

WebCullin 3 (CUL3) is a member of cullin protein family and is encoded by the gene mapped to human chromosome 2q36.2. The encoded protein is a core component of cullin/RING … WebOct 27, 2024 · Treatment with DI-591 selectively converts cellular cullin 3 into an un-neddylated inactive form with no or minimum effect on other cullin members. ... anti-DCN1 (GWB-E3D700) antibody from GenWay ... WebCullin 1 Antibody (32-2400) in WB Western blot analysis was performed on whole cell, tissue extracts (30 µg lysate) of HEL 92.1.7 (Lane 1), MDA-MB-231 (Lane 2), NTERA-2 … novant health university charlotte nc

A potent small-molecule inhibitor of the DCN1-UBC12 ... - Nature

Category:Cullin 3 and Its Role in Tumorigenesis - PubMed

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Cullin 3 antibody

Cullin 1 Monoclonal Antibody (2H4C9) - Thermo Fisher …

WebCullin 3 (CUL3) is a member of cullin protein family and is encoded by the gene mapped to human chromosome 2q36.2. The encoded protein is a core component of cullin/RING E3 ubiquitin ligase (CRL) and is ubiquitously expressed. The protein is characterized with a cullin homology domain. [ 1] [ 2] WebCullin 3 antibody (ABIN5622396). Validated for ICC, IF, WB. Tested in Human, Mouse. Order online.

Cullin 3 antibody

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WebView Rabbit Polyclonal anti-Cullin 3 Antibody (NBP2-88799). Validated Applications: WB. Validated Species: Human. Skip to main content Support: 1-888-506-6887 Items in Cart … WebAll lanes : Anti-Cullin 3/CUL-3 antibody [EPR3195] at 1/5000 dilution Lane 1 : HeLa cell lysate Lane 2 : SH-SY5Y cell lysate Lane 3 : PC12 cell lysate Lane 4 : NIH 3T3 cell lysate Lysates/proteins at 10 µg per lane. Predicted band size: 89 kDa. This data was developed using ab108407, the same antibody clone in a different buffer formulation.

WebCUL3 (Cullin-3) ubiquitin ligase complex targets multiple substrate for ubiquitination including cyclin E and of cyclin D1. Defects in CUL3 are the cause of Pseudohypoaldosteronism type 2E (PHA2E) characterized by … WebThe CUL3 gene provides instructions for making a protein called cullin-3. This protein plays a role in the cell machinery that breaks down (degrades) unwanted proteins, called the ubiquitin-proteasome system. Cullin-3 is a core piece of a complex known as an E3 ubiquitin ligase. E3 ubiquitin ligases function as part of the ubiquitin-proteasome ...

WebMar 29, 2024 · Cullin3 (CUL3) suppresses proliferation, migration and phenotypic transformation of PDGF-BB-stimulated vascular smooth muscle cells and mitigates inflammatory response by repressing Hedgehog signaling pathway. Xiang Y, et al. Bioengineered, 2024 Dec. PMID 34699319, Free PMC Article WebHome; Products. Featured Collections. Recombinant Rabbit Monoclonal Antibodies; IHC/Pathology Antibodies; KO Validated Antibodies; Antibodies. Primary Antibodies

WebRabbit Cullin 3 Rabbit mAb (A19623), validaed in WB,IHC and tested in Human,, Mouse,, Rat. 100% Guaranteed. ABclonal provides trial size antibody samples for target detection. Replacement to Abcam, Santa Cruz, Sigma and CST antibody.

WebII. Primary Antibody Incubation. Incubate membrane and primary antibody (at the appropriate dilution and diluent as recommended in the product webpage) in 10 ml … how to smoke kief with pipeWebNEDD8 Antibody detects endogenous levels of total NEDD8. RRID: AB_2838263 引用格式: Affinity Biosciences Cat# DF6297, RRID:AB_2838263. ... is also required for neddylation of the cullin proteins (6). Protein de-neddylation is catalyzed by a number of enzymes in the cell, including a ubiquitin-specific protease USP21, the NEDP1/DEN1 ... novant health uptown charlotteWebGeneral notes. This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved … how to smoke live diamondsWebAnti-Cullin 3/CUL-3 antibody See all Cullin 3/CUL-3 primary antibodies Description Rabbit polyclonal to Cullin 3/CUL-3 Host species Rabbit Tested applications Suitable for: IHC-P more details Species reactivity Reacts with: Human Predicted to … how to smoke kingfishWebCullin 3 is a member of the family of human Cullin genes (CUL-1, -2, -3, -4a, -4b and -5) homologous to the S. cerevisiae cdc53 gene. Cullin 3 … novant health university executive parkWebCullin-3 belongs to the cullin family of hydrophobic proteins that confer substrate specificity to the multimeric Cullin-RING E3 ubiquitin ligase (CRL) complexes by acting as scaffold … how to smoke live resin badderWebBoster Bio Anti-Cullin 3/CUL3 Antibody catalog # PA1939. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. Supplied as 100μg/vial in Lyophilized form … novant health uptown